References
Adiponectin, an adipocytokine secreted by adipose tissue, enhances insulin sensitivity and inhibits vascular inflammation. Hypoadiponectinemia is associated with endothelial dysfunction, hypertension, coronary heart disease, and other cardiovascular complications. Furthermore, enhancing adiponectin concentrations by lifestyle changes or pharmacological therapy can have cardiovascular-protective effects. In this chapter, we review the association between adiponectin and cardiovascular disease and discuss treatment strategies to ameliorate hypoadiponectinemia.