Taking into account data obtained primarily from 1996 to 2008, this paper reviews the importance of Doñana Natural Space for seven species of waterbird declared “Endangered”: the highest category of threat from a legal perspective in Spain. Marbled teal, ferruginous duck, white-headed duck, bittern, squacco heron, and red-knobbed coot all breed, while black stork has a wintering population. Only the winter population of the black stork showed a significant trend, positive in this case. The wetlands of Doñana Natural Space represent the first or second most important areas of Spain for all the breeding species except white-headed duck.