Abstract The Almadn district is the largest mercury concentration in the world, with a total content of about 250000t of mercury, nearly one third of the known total mercury resources of the Earth. Mercury has been exploited since the Celtic and Roman times, with peak production during the Renaissance and between 19391945. The district is hosted by a Paleozoic synclinorium overlying Precambrian rocks. The Paleozoic sequence comprises epicontinental quartz arenite rocks, including black shales and quartzites. Diatremes, alkaline lavas of different composition, and late tholeiitic diabases account for the Ordovician to Devonian magmatism. The tectonic setting of this complex suite corresponds to the intraplate type. The mercury deposits of Almadn can be classified into two main types: type 1, early stratiform type ores characterized by cinnabar deposition on the lower Silurian quartzites (Criadero quartzite; e.g. the Almadn and El Entredicho deposits), and type 2, late discordant orebodies (e.g. Las Cuevas), largely hosted or related to diatremes (the `frailesca rocks) of alkaline basaltic composition. In type 1 cinnabar was deposited during diagenesis, in relation to hydrothermal circulation driven by magmatic activity. Type 2 include a variety of deposits having in common the discordant character of the orebodies (e.g. veins, stockworks, massive replacements), and their wide dispersion along the stratigraphic column, i.e. from Lower Silurian (e.g. Nueva Concepcin) to Upper Devonian (e.g. Corchuelo).