Isolating the sensitive equipment from vibrating base or the foundation from machinery vibration is of practical importance in a number of engineering fields. With the development of the vibration control techniques and increasing requirements for the higher-performance vibration isolation in industry and everyday life, active vibration isolation exhibits the best performances. In this paper, active vibration isolation reducing vibration transmitted from vibrating base to sensitive equipment and from machinery to foundation was investigated. Controller as static output feedback was considered to design components of active isolation system. An active control is provided by using H ∞ control criteria to design this controller. This criterion is presented as a cost function and then optimized by Particle Swarm Optimization (PSO) algorithm. The approach is validated using numerical simulation. Results show that this static output feedback H ∞ controller using PSO algorithm can get good performance to reduce the effect of unwanted vibration and disturbances.