A new way of devising numerical methods is introduced whose distinctive feature is the computation of a finite element approximation only in a polyhedral subdomain of the original, possibly curved-boundary domain. The technique is applied to a discontinuous Galerkin method for the one-dimensional diffusion-reaction problem. Sharp a priori error estimates are obtained which identify conditions, on the subdomain and the discretization parameters of the discontinuous Galerkin method, under which the method maintains its original optimal convergence properties. The error analysis is new even in the case in which . It allows to see that the uniform error at any given interval is bounded by an interpolation error associated to the interval plus a significantly smaller error of a global nature. Numerical results confirming the sharpness of the theoretical results are displayed. Also, preliminary numerical results illustrating the application of the method to two-dimensional second-order elliptic problems are shown.