Hybrid configurations between aluminium and steel are needed to meet today’s requirements for lightweight construction in the automotive industry. Different studies showed that Friction Stir Welding (FSW) as well as Friction Stir Spot Welding (FSSW) processes are suitable for joining aluminium to steel. In this work, dissimilar FSSW of aluminium AA5754 and galvanised steel HX 340LAD were examined. In particular the influence of different spindle speeds and dwell times on microstructure and the mechanical properties of the weld were analysed. In doing so, the cross-section microstructure of the weld interface was observed by light optical microscope (LOM) and scanning electron microscope (SEM). The strength of the welds was evaluated both by tensile shear and vibration fatigue tests. The influences of the individual parameters on the weld are presented in detail. The appearance of intermetallic phases (IMPs), a severe problem for conventional fusion welding processes between aluminium and steel, were investigated for the welded samples and a link to the mechanical properties is given.