In this paper, a research model and some hypotheses with regard to the effects of supply chain globalization on quality management and firm performance are proposed based on a comprehensive literature review. Structural equation modeling (SEM) techniques are employed to test the conceptual model by using empirical data that were collected from practicing managers of firms operating in Shanghai, China. The findings show that global supply chain management is significantly correlated with the quality management and, directly and indirectly influences positively firm performance. The implications of the findings for researchers and practitioners are further discussed.