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Growth hormone deficiency (GHD) in patients is diagnosed as an isolated finding or in combination with other pituitary hormone deficiencies and classified as combined pituitary hormone deficiency (CPHD). Although any type of neurological insult such as trauma, radiation, or surgery place the pituitary at risk for injury and potential destruction of somatotrophs, a subgroup of patients develop idiopathic...
Until the advent of magnetic resonance imaging (MRI), only small advances were made in the field of pituitary imaging. MRI, however, led to an enormous increase in our detailed knowledge of pituitary morphology, thus improving the differential diagnosis of hypopituitarism. Indeed, MRI represents the examination method of choice for evaluating hypothalamic-pituitary-related endocrine diseases thanks...
Pituitary adenomas are benign intracranial neoplasms and clinically apparent pituitary adenomas have a prevalence of approximately 1:1,000 individuals. They usually arise sporadically, but familial pituitary adenomas comprise about 5% of all cases, more than half of which include multiple endocrine neoplasia type 1 (MEN1) and Carney complex (CNC). The other half is represented by familial isolated...
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