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Background Radiomics suffers from feature reproducibility. We studied the variability of radiomics features and the relationship of radiomics features with tumor size and shape to determine guidelines for optimal radiomics study. Methods We dealt with 260 lung nodules (180 for training, 80 for testing) limited to 2 cm or less. We quantified how voxel geometry (isotropic/anisotropic) and the number...
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