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Network-based approaches to human disease have diverse biological and clinical applications. A more appropriate interpretation of biological interconnectivity with disease progression could possibly lead to identification of disease pathways and disease genes. This, in turn, helps in accurate prediction of biomarkers and targets for drug development. This study is a large-scale system-level network...
A set of correlated and co-expressed genes, often referred as a functional module, play a synergistic role during any disease or any biological activities. Genes participating in a common module may cause clinically similar diseases and share a common genetic origin of their associated disease phenotypes. Identifying such modules may be helpful in system-level understanding of biological and cellular...
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