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Metal stents have been very effective medical devices for coronary artery disease. On the other hand, hyperplasia proliferation of smooth muscle cells and late thrombus formation are the main causes of stent failure. To solve the problem, an anti-platelet/anti-proliferative drug, ReoRro, was used as a target drug for a drug-eluting stent (DES). An emulsion consisting of poly(lactic-co-glycolic acid)...
Endothelial cell-coated stents have attracted interest as an ideal treatment method for preventing restenosis following stent deployment to the peripheral locations. In an attempt to evaluate the proliferation and differentiation activities of human umbilical vein endothelial cells (HUVECs), the acetylated polysaccharide, pullulan acetate (PA), loaded with vascular endothelial growth factor (VEGF)...
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