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A 76-year-old Asian man with a 6-month history of intractable watery diarrhea proceeded to colonoscopic examination that revealed diffusely dull-appearing colonic mucosa with focal areas of superficial ulceration. Mucosal biopsies demonstrated a neoplastic population of monomorphous small-to-intermediate-sized CD8+/CD56+ cytotoxic T cells that densely infiltrated the surface epithelium and crypts...
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