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Low-frequency ultrasound (LFU) irradiation under certain acoustic intensity can increase blood–brain barrier permeability non-invasively and reversibly. The aim of this study was to find out the effect of LFU irradiation on blood–tumor barrier (BTB) permeability in rat C6 glioma model and the possible mechanism. In this research, Evans blue and H&E staining were used to evaluate the optimal parameter...
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