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Ovarian follicles from days 13, 14, 15, and 16 and corpora lutea (CL) from days 2, 4, 8, 12, and 15 of the estrous cycle were evaluated for the presence of connexins by immunohistochemistry. In addition, CL from days 5, 10, and 15 of the estrous cycle were used for immunofluorescent detection of Cx43 followed by image analysis, and for Western immunoblot. In all tissues, staining for all connexins...
Insulin-like growth factor binding protein-2 (IGFBP-2), the predominant IGFBP in the fetal circulation and an induced protein during several types of malignancies, belongs to a family of structurally related proteins that bind the mitogens, IGF-1 and IGF-2. The present study focused on functional analysis of the 5′-flanking region (∼1.3 kb) of the IGFBP-2 gene to identity nuclear factors that mediate...
This study investigates the insulin secretory responsiveness of pancreatic islets to repaglinide in an experimental model of B-cell glucose incompetence. Rats were infused for 2 d with a 1.67 M solution of d-glucose administered at a rate close to 2.8 mL/h. This resulted in a modest rise in glycemia, a severe increase in plasma insulin concentration, an increased sensitivity of B-cells to adrenergic...
Although neurotransmitters are present in pancreatic islets of Langerhans and can be shown to alter hormone secretion, their precise physiological roles in islet function and their cellular mechanisms of action are unclear. Recent research has identified specific neurotransmitter receptor isoforms in islets that may be important physiologically, because selective receptor agonists activate islet ion...
Erythropoietin (EPO) is a glycoprotein hormone produced primarily in the kidneys and to a lesser extent in the liver that regulates red cell production. Most of the studies conducted in experimental animals to assess the role of EPO in the regulation of erythropoiesis were performed in mouse models. However, little is known about the in vivo metabolism of the hormone in this species. The present study...
Through selective activation of the gonadotropic signal transduction pathway, we have determined the probable site of the antigonadotropic effects of prostaglandin F2α (PGF2α) in the human granulosa-luteal cell (hGLC). The gonadotropic signal transduction pathway was activated at the level of the receptor (luteinizing hormone and β-adrenergic), stimulatory G protein (Gs), adenylate cyclase (AC), and...
The biosynthesis of met-enkephalin in human pituitary and human pituitary adenomas is still not well known. In this work, we studied the processing of proenkephalin-derived peptides in postmortem human pituitary (PMHP), ACTH-producing adenomas (ACTH-PA), nonfunctioning adenomas (NFA), and GH-producing adenomas (GH-PA). ACTH-PA contained at least 10 times more proenkephalin-derived peptides than PMHP,...
This study examined the effects of prostaglandin F2α (PGF2α) and human chorionic gonadotropin (hCG) on the levels of PGF2α-receptor (PGF2α-R) mRNA and steroidogenesis, in the human granulosa luteal cell (hGLC). Human GLCs collected from patients undergoing in vitro fertilization, were cultured for 24 h, after which cells were exposed to culture media containing either vehicle, hCG (1 IU/mL), or hCG...
To determine whether murine mammary growth is modulated by local insulin-like growth factor-1 (IGF-1) production, expression of recombinant IGF-1 was directed to the mammary glands of transgenic mice using an ovine prepro IGF-1 cDNA under control of the mouse mammary tumor virus-long terminal repeat (MMTV-LTR) promoter. Bioactivity of recombinant IGF-1 in transgenic mouse milk extracts was demonstrated...
Parathyroid hormone-related protein (PTHrP) is produced by a wide range of neoplastic and normal cells, including keratinocytes where it may regulate growth and differentiation. Transforming growth factor-β (TGF-β) is a growth factor produced by many cells, including keratinocytes where it regulates epidermal homeostasis. TGF-β has been reported to be cosecreted with PTHrP in some neoplasms and to...
Activation of the sympathetic innervation precedes the induction of polycystic ovaries in rats given estradiol valerate (EV). The mechanism of induction by EV may thus involve both direct and neurogenic components. We tested this hypothesis using a combined cold and restraint stress to induce an increase in sympathetic tone, including that of the ovarian sympathetic nerves. Three weeks after the start...
Assisted reproductive technologies (ART) have received considerable attention, both clinically and empirically. Drs. Steptoe and Edwards removed one oocyte surgically from a woman with infertility related to tubal disease. They fertilized this oocyte in vitro and transferred the formed embryo to the woman’s uterus and achieved pregnancy and delivery. The technique of in vitro fertilization (IVF) and...
Androgens and the androgen receptor (AR) both play critical roles for the development of the male phenotype. To investigate the roles of androgens in the developing nervous system, we examined the AR messenger RNA distribution by in situ hybridization. Our results indicate that AR transcripts were detectable in male mouse embryos at embryonic day 11 (E11). Intensive AR labeling appears in the neuroepithelium...
The pathogenesis of benign prostatic hyperplasia is linked to the accumulation of dihydrotestosterone (DHT), the active form of testosterone (T), in prostatic tissue. We have defined characteristics of 5α-reductase enzyme which catalyzes the conversion of T into DHT in prostatic microsomes of growing pigs. Peaks for the 5α-reductase activity were found at pH 5.5 and 8.0, which indicates the presence...
A hormone response element, CNTFRα-NBRE (5′-AAAGGTCA-3′) has been identified in the fifth intron of the α component of ciliary neurotrophic factor receptor gene (CNTFR-I5) for the human TR3 orphan receptor (TR3). A specific binding between in vitro expressed TR3 and CNTFRα-NBRE was demonstrated by using electrophoretic mobility shift assay. A reporter gene assay using chloramphenicol acetyltransferase...
Serotonin is known to stimulate prolactin secretion by decreasing tyrosine hydroxylase (TH) activity in the tuberoinfundibular dopaminergic (TIDA) neurons. However, the effects of aging on the responsiveness of TIDA neurons to serotonin are not known. An effective way to increase serotonergic activity is to administer 5-hydroxytryptophan (5-HTP), a serotonin precursor. The present study was done to...
99mTc-sesta-(2-methoxy-isobutyl-isonitrile) (Tc-MIBI) is currently used for imaging of several organs. In the present study, its uptake by rat pancreatic islets, rat parotid cells, and human breast adenocarcinoma cells (MCF-7 cells) was found to be grossly proportional to its concentration (up to 0.1 µM), time-related (with a fractional turnover rate close to 2–3 10−2 · min−1), and stimulated by...
Noninsulin-depenent diabetes mellitus (NIDDM), a major health care problem in the Western world, is a disease typified by a relative deficiency of insulin, leading to vast derangements in glucose and lipid homeostasis with disastrous vascular complications. Despite immense research efforts aimed at a clear understanding of the etiology of this complex disease, the molecular mechanisms causing the...
Effect of growth hormone-releasing peptide-2 (GHRP-2) on ovine somatotrophs is abolished by a growth hormone-releasing factor (GRF) receptor antagonist, which raises the possibility that GHRP-2 may act on GRF receptors. In the present study, we used rat pituitary GC cells with or without stable transfection of cDNA coding for the human GRF receptor (GC/R+ or GC/R−) to determine whether or not GHRP-2...
In these studies, we show that endothelin (ET), leukemia inhibitory factor (LIF), phenylephrine (PE), and prostaglandin F2α(PGF2α), which are all hypertrophic for neonatal rat cardiac myocytes in culture, induce distinct morphological, physiological, and genetic changes after a 48-h treatment. Transmission electron microscopy revealed differences in myofibril organization, with ET-treated cells containing...
FreeMarker template error (HTML_DEBUG mode; use RETHROW in production!)
Java method "org.springframework.web.servlet.support.RequestContext.getMessage(String)" threw an exception when invoked on org.springframework.web.servlet.support.RequestContext object "org.springframework.web.servlet.support.RequestContext@3ccd0ab5"; see cause exception in the Java stack trace.
----
FTL stack trace ("~" means nesting-related):
- Failed at: ${springMacroRequestContext.getMessag... [in template "META-INF/freemarker-templates/spring.ftl" in macro "message" at line 28, column 22]
- Reached through: @spring.message "portal.searchResult... [in template "META-INF/freemarker-templates/portal/search/facets.ftl" at line 149, column 33]
----
Java stack trace (for programmers):
----
freemarker.core._TemplateModelException: [... Exception message was already printed; see it above ...]
at freemarker.ext.beans._MethodUtil.newInvocationTemplateModelException(_MethodUtil.java:289)
at freemarker.ext.beans._MethodUtil.newInvocationTemplateModelException(_MethodUtil.java:261)
at freemarker.ext.beans.OverloadedMethodsModel.exec(OverloadedMethodsModel.java:65)
at freemarker.core.MethodCall._eval(MethodCall.java:65)
at freemarker.core.Expression.eval(Expression.java:81)
at freemarker.core.DollarVariable.calculateInterpolatedStringOrMarkup(DollarVariable.java:96)
at freemarker.core.DollarVariable.accept(DollarVariable.java:59)
at freemarker.core.Environment.visit(Environment.java:363)
at freemarker.core.Environment.invoke(Environment.java:715)
at freemarker.core.UnifiedCall.accept(UnifiedCall.java:83)
at freemarker.core.Environment.visit(Environment.java:327)
at freemarker.core.Environment.visit(Environment.java:333)
at freemarker.core.Environment.visit(Environment.java:369)
at freemarker.core.IteratorBlock$IterationContext.executedNestedContentForCollOrSeqListing(IteratorBlock.java:316)
at freemarker.core.IteratorBlock$IterationContext.executeNestedContent(IteratorBlock.java:272)
at freemarker.core.IteratorBlock$IterationContext.accept(IteratorBlock.java:243)
at freemarker.core.Environment.visitIteratorBlock(Environment.java:596)
at freemarker.core.IteratorBlock.acceptWithResult(IteratorBlock.java:108)
at freemarker.core.IteratorBlock.accept(IteratorBlock.java:94)
at freemarker.core.Environment.visit(Environment.java:327)
at freemarker.core.Environment.visit(Environment.java:333)
at freemarker.core.Environment.visit(Environment.java:333)
at freemarker.core.Environment.visit(Environment.java:333)
at freemarker.core.Environment.process(Environment.java:306)
at freemarker.ext.servlet.FreemarkerServlet.processEnvironment(FreemarkerServlet.java:910)
at freemarker.ext.servlet.FreemarkerServlet.process(FreemarkerServlet.java:879)
at freemarker.ext.servlet.FreemarkerServlet.doGet(FreemarkerServlet.java:764)
at org.apache.tiles.request.freemarker.render.FreemarkerRenderer.render(FreemarkerRenderer.java:73)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:259)
at org.apache.tiles.template.InsertAttributeModel.renderAttribute(InsertAttributeModel.java:188)
at org.apache.tiles.template.InsertAttributeModel.execute(InsertAttributeModel.java:132)
at org.apache.tiles.jsp.taglib.InsertAttributeTag.doTag(InsertAttributeTag.java:299)
at freemarker.ext.jsp.SimpleTagDirectiveModel.execute(SimpleTagDirectiveModel.java:92)
at freemarker.core.Environment.visit(Environment.java:427)
at freemarker.core.UnifiedCall.accept(UnifiedCall.java:101)
at freemarker.core.Environment.visit(Environment.java:327)
at freemarker.core.Environment.visit(Environment.java:333)
at freemarker.core.Environment.process(Environment.java:306)
at freemarker.ext.servlet.FreemarkerServlet.processEnvironment(FreemarkerServlet.java:910)
at freemarker.ext.servlet.FreemarkerServlet.process(FreemarkerServlet.java:879)
at freemarker.ext.servlet.FreemarkerServlet.doGet(FreemarkerServlet.java:764)
at org.apache.tiles.request.freemarker.render.FreemarkerRenderer.render(FreemarkerRenderer.java:73)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:259)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:397)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:238)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:221)
at org.apache.tiles.renderer.DefinitionRenderer.render(DefinitionRenderer.java:59)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:259)
at org.apache.tiles.template.InsertAttributeModel.renderAttribute(InsertAttributeModel.java:188)
at org.apache.tiles.template.InsertAttributeModel.execute(InsertAttributeModel.java:132)
at org.apache.tiles.jsp.taglib.InsertAttributeTag.doTag(InsertAttributeTag.java:299)
at freemarker.ext.jsp.SimpleTagDirectiveModel.execute(SimpleTagDirectiveModel.java:92)
at freemarker.core.Environment.visit(Environment.java:427)
at freemarker.core.UnifiedCall.accept(UnifiedCall.java:101)
at freemarker.core.Environment.visit(Environment.java:327)
at freemarker.core.Environment.visit(Environment.java:333)
at freemarker.core.Environment.process(Environment.java:306)
at freemarker.ext.servlet.FreemarkerServlet.processEnvironment(FreemarkerServlet.java:910)
at freemarker.ext.servlet.FreemarkerServlet.process(FreemarkerServlet.java:879)
at freemarker.ext.servlet.FreemarkerServlet.doGet(FreemarkerServlet.java:764)
at org.apache.tiles.request.freemarker.render.FreemarkerRenderer.render(FreemarkerRenderer.java:73)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:259)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:397)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:238)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:221)
at org.apache.tiles.renderer.DefinitionRenderer.render(DefinitionRenderer.java:59)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:259)
at org.apache.tiles.template.InsertAttributeModel.renderAttribute(InsertAttributeModel.java:188)
at org.apache.tiles.template.InsertAttributeModel.execute(InsertAttributeModel.java:132)
at org.apache.tiles.jsp.taglib.InsertAttributeTag.doTag(InsertAttributeTag.java:299)
at freemarker.ext.jsp.SimpleTagDirectiveModel.execute(SimpleTagDirectiveModel.java:92)
at freemarker.core.Environment.visit(Environment.java:427)
at freemarker.core.UnifiedCall.accept(UnifiedCall.java:101)
at freemarker.core.Environment.visit(Environment.java:327)
at freemarker.core.Environment.visit(Environment.java:333)
at freemarker.core.Environment.process(Environment.java:306)
at freemarker.ext.servlet.FreemarkerServlet.processEnvironment(FreemarkerServlet.java:910)
at freemarker.ext.servlet.FreemarkerServlet.process(FreemarkerServlet.java:879)
at freemarker.ext.servlet.FreemarkerServlet.doGet(FreemarkerServlet.java:764)
at org.apache.tiles.request.freemarker.render.FreemarkerRenderer.render(FreemarkerRenderer.java:73)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:259)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:397)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:238)
at org.apache.tiles.impl.BasicTilesContainer.render(BasicTilesContainer.java:221)
at org.apache.tiles.renderer.DefinitionRenderer.render(DefinitionRenderer.java:59)
at org.springframework.web.servlet.view.tiles3.TilesView.renderMergedOutputModel(TilesView.java:132)
at pl.edu.icm.synat.common.ui.tiles.FreeMarkerAndTilesView.renderMergedOutputModel(FreeMarkerAndTilesView.java:148)
at org.springframework.web.servlet.view.AbstractView.render(AbstractView.java:303)
at org.springframework.web.servlet.DispatcherServlet.render(DispatcherServlet.java:1243)
at org.springframework.web.servlet.DispatcherServlet.processDispatchResult(DispatcherServlet.java:1027)
at org.springframework.web.servlet.DispatcherServlet.doDispatch(DispatcherServlet.java:971)
at org.springframework.web.servlet.DispatcherServlet.doService(DispatcherServlet.java:893)
at org.springframework.web.servlet.FrameworkServlet.processRequest(FrameworkServlet.java:965)
at org.springframework.web.servlet.FrameworkServlet.doGet(FrameworkServlet.java:856)
at javax.servlet.http.HttpServlet.service(HttpServlet.java:620)
at org.springframework.web.servlet.FrameworkServlet.service(FrameworkServlet.java:841)
at javax.servlet.http.HttpServlet.service(HttpServlet.java:727)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:303)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
at org.apache.tomcat.websocket.server.WsFilter.doFilter(WsFilter.java:52)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:316)
at org.springframework.security.web.access.intercept.FilterSecurityInterceptor.invoke(FilterSecurityInterceptor.java:126)
at org.springframework.security.web.access.intercept.FilterSecurityInterceptor.doFilter(FilterSecurityInterceptor.java:90)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.access.ExceptionTranslationFilter.doFilter(ExceptionTranslationFilter.java:114)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.session.SessionManagementFilter.doFilter(SessionManagementFilter.java:122)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.authentication.AnonymousAuthenticationFilter.doFilter(AnonymousAuthenticationFilter.java:111)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.authentication.rememberme.RememberMeAuthenticationFilter.doFilter(RememberMeAuthenticationFilter.java:149)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.servletapi.SecurityContextHolderAwareRequestFilter.doFilter(SecurityContextHolderAwareRequestFilter.java:168)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.savedrequest.RequestCacheAwareFilter.doFilter(RequestCacheAwareFilter.java:48)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.FilterChainProxy.doFilterInternal(FilterChainProxy.java:207)
at org.springframework.security.web.FilterChainProxy.doFilter(FilterChainProxy.java:184)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.authentication.AbstractAuthenticationProcessingFilter.doFilter(AbstractAuthenticationProcessingFilter.java:205)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.jasig.cas.client.session.SingleSignOutFilter.doFilter(SingleSignOutFilter.java:100)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.authentication.AbstractAuthenticationProcessingFilter.doFilter(AbstractAuthenticationProcessingFilter.java:205)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.authentication.logout.LogoutFilter.doFilter(LogoutFilter.java:120)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.authentication.logout.LogoutFilter.doFilter(LogoutFilter.java:120)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.header.HeaderWriterFilter.doFilterInternal(HeaderWriterFilter.java:64)
at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.context.request.async.WebAsyncManagerIntegrationFilter.doFilterInternal(WebAsyncManagerIntegrationFilter.java:53)
at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.session.ConcurrentSessionFilter.doFilter(ConcurrentSessionFilter.java:133)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.context.SecurityContextPersistenceFilter.doFilter(SecurityContextPersistenceFilter.java:91)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.access.channel.ChannelProcessingFilter.doFilter(ChannelProcessingFilter.java:152)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.saml.metadata.MetadataGeneratorFilter.doFilter(MetadataGeneratorFilter.java:87)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at pl.edu.icm.synat.portal.web.security.PortalLocaleFilter.doFilterInternal(PortalLocaleFilter.java:51)
at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
at org.springframework.security.web.FilterChainProxy$VirtualFilterChain.doFilter(FilterChainProxy.java:330)
at org.springframework.security.web.FilterChainProxy.doFilterInternal(FilterChainProxy.java:213)
at org.springframework.security.web.FilterChainProxy.doFilter(FilterChainProxy.java:176)
at org.springframework.web.filter.DelegatingFilterProxy.invokeDelegate(DelegatingFilterProxy.java:344)
at org.springframework.web.filter.DelegatingFilterProxy.doFilter(DelegatingFilterProxy.java:261)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
at ch.qos.logback.classic.helpers.MDCInsertingServletFilter.doFilter(MDCInsertingServletFilter.java:51)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
at org.springframework.web.filter.CharacterEncodingFilter.doFilterInternal(CharacterEncodingFilter.java:85)
at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
at pl.edu.icm.synat.portal.web.security.RemoteIpFilter.doFilter(RemoteIpFilter.java:75)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
at net.bull.javamelody.MonitoringFilter.doFilter(MonitoringFilter.java:219)
at net.bull.javamelody.MonitoringFilter.doFilter(MonitoringFilter.java:196)
at org.apache.catalina.core.ApplicationFilterChain.internalDoFilter(ApplicationFilterChain.java:241)
at org.apache.catalina.core.ApplicationFilterChain.doFilter(ApplicationFilterChain.java:208)
at org.apache.catalina.core.StandardWrapperValve.invoke(StandardWrapperValve.java:220)
at org.apache.catalina.core.StandardContextValve.invoke(StandardContextValve.java:122)
at org.apache.catalina.authenticator.AuthenticatorBase.invoke(AuthenticatorBase.java:504)
at org.apache.catalina.core.StandardHostValve.invoke(StandardHostValve.java:170)
at org.apache.catalina.valves.ErrorReportValve.invoke(ErrorReportValve.java:103)
at org.apache.catalina.core.StandardEngineValve.invoke(StandardEngineValve.java:116)
at org.apache.catalina.connector.CoyoteAdapter.service(CoyoteAdapter.java:421)
at org.apache.coyote.ajp.AjpProcessor.process(AjpProcessor.java:190)
at org.apache.coyote.AbstractProtocol$AbstractConnectionHandler.process(AbstractProtocol.java:611)
at org.apache.tomcat.util.net.JIoEndpoint$SocketProcessor.run(JIoEndpoint.java:314)
at java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1142)
at java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:617)
at org.apache.tomcat.util.threads.TaskThread$WrappingRunnable.run(TaskThread.java:61)
at java.lang.Thread.run(Thread.java:745)
Caused by: org.springframework.context.NoSuchMessageException: No message found under code 'portal.searchResult.facet.^journalYear^journalVolume^journalNumber' for locale 'pl'.
at org.springframework.context.support.AbstractMessageSource.getMessage(AbstractMessageSource.java:159)
at org.springframework.context.support.DelegatingMessageSource.getMessage(DelegatingMessageSource.java:66)
at org.springframework.context.support.AbstractApplicationContext.getMessage(AbstractApplicationContext.java:1129)
at org.springframework.web.servlet.support.RequestContext.getMessage(RequestContext.java:712)
at org.springframework.web.servlet.support.RequestContext.getMessage(RequestContext.java:678)
at sun.reflect.GeneratedMethodAccessor295.invoke(Unknown Source)
at sun.reflect.DelegatingMethodAccessorImpl.invoke(DelegatingMethodAccessorImpl.java:43)
at java.lang.reflect.Method.invoke(Method.java:497)
at freemarker.ext.beans.BeansWrapper.invokeMethod(BeansWrapper.java:1458)
at freemarker.ext.beans.ReflectionCallableMemberDescriptor.invokeMethod(ReflectionCallableMemberDescriptor.java:56)
at freemarker.ext.beans.MemberAndArguments.invokeMethod(MemberAndArguments.java:51)
at freemarker.ext.beans.OverloadedMethodsModel.exec(OverloadedMethodsModel.java:61)
... 179 more