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Nephrolithiasis is a major cause of morbidity involving the urinary tract. The prevalence of this disease in the United States increased from 3.8% in the 1970s to 5.2% in the 1990s. There were nearly 2 million physician office visits for nephrolithiasis in 2000, and estimated annual costs totaled $2 billion. About 80% of stones are composed of calcium oxalate with variable amounts of calcium phosphate...
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