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Sulforaphane, a cruciferous isothiocyanate compound, upregulates cytoprotective genes in liver, but its effects on antioxidants and phase 2 defenses in vascular cells are unknown. Here we report that incubation of rat aortic smooth muscle A10 cells with sulforaphane (0.25–5 μM) resulted in concentration-dependent induction of a spectrum of important cellular antioxidants and phase 2 enzymes, including...
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