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Background and aims Phase 3 trials have shown the efficacy of vedolizumab, which binds to integrin α4-β7, in patients with Crohn’s disease (CD) or ulcerative colitis (UC). We investigated the effectiveness and safety of vedolizumab in patients who failed anti-tumor necrosis factor therapy. Methods From June through December 2014, there were 173 patients with CD and 121 patients with UC who were...
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