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The unfertilized oocyte is surrounded by a spherical layer called the zona pellucida (ZP). The physical hardness of this layer plays a crucial role in fertilization and it is largely unknown because of the lack of appropriate measuring and modeling methods. Recently, considerable biomedical attentions have concentrated on determination of the mechanical properties of oocytes as a single cell. In order...
Determination of the mechanical properties of individual sand grains by conventional material testing methods at the macroscale is somewhat difficult due to the sizes of the individual sand particles (a few μm to mm). In this paper, we used the nanoindentation technique with a Berkovich tip to measure the Young’s modulus, hardness, and fracture toughness. An inverse problem solving approach was adopted...
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