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This paper addresses the possibility of mathematically partition and process urine 1H-NMR spectra to enhance the efficiency of the subsequent multivariate data analysis in the context of metabolic profiling of a toxicity study. We show that by processing the NMR data with the peak alignment using reduced set mapping (PARS) algorithm and the use of sparse representation of the data results in the information...
The objective measurement of chronic pain in pre-clinical animal models and in the clinical arena is problematic. The multifactorial nature of pain can adversely affect the accuracy with which it can be quantitatively assessed. This is due to diverse aetiology, environmental factors and psychological status which can significantly affect the measurement of pain in animal models and presentation in...
Introduction Meningitis, a morbidly infectious central nervous system pathology is accompanied by acute inflammation of the meninges, causing raised intracranial pressure linked with serious neurological sequelae. Objective To observe the variation in the metabolic profile, that may occur in serum and urine along with CSF in adults using 1H NMR spectroscopy, with an attempt of appropriate and timely...
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