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Methyl pheophorbide a reacts with terpene alcohols on activation with the Mukaiyama reagent to give the products of the formal transesterification of the C(21)CO2Me group. To increase hydrophilicity, the synthesized conjugates were modified following two different paths. The first path is the acid-catalyzed transesterification of the C(3)(CH2)2CO2Me moiety of the conjugate with triethylene glycol...
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