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Objective Different variants of time trade-off (TTO) have been employed to elicit health state preferences and to create value sets for preference-based instruments. We compared composite TTO (cTTO) with traditional TTO (tTTO) in valuing severe EQ-5D-5L health states. Methods cTTO uses tTTO to elicit values for health states better than dead and the lead-time TTO for states worse than dead. Eighteen...
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