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Geminiviruses have recently emerged not only as the cause of devastating diseases of important crop plants but also as a tool to study fundamental aspects of RNA interference (RNAi) and virus-induced gene silencing. RNA silencing is an evolutionary conserved mechanism protecting cell from pathogenic RNA and DNA, which is increasingly viewed as an adaptive immune system of plants against viruses. Here...
Geminiviruses are ssDNA viruses that infect a range of economically important crop species. We have developed a pathogen-derived transgenic approach to generate high levels of resistance against these pathogens in a susceptible cultivar of cassava (Manihot esculenta). Integration of the AC1 gene (which encodes the replication-associated protein) from African cassava mosaic virus imparted resistance...
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