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Low-intensity high-frequency stimulation (HFS) delivered to the basolateral nuclei of the amygdala (BLAs) induced anti-nociceptive effects and reduced spontaneous motor activities in freely moving rats. Stimulation (20 μA, 100 sec–1, 200 μsec square, for 30 sec) was applied through electrodes implanted bilaterally in the BLA. Pain behavioral responses were inhibited by HFS in the formalin test but...
We examined the effects of propentofylline (PPF) injected intracerebroventricularly (i.c.v., 30 mM, 10 μl) into female Sprague–Dawley rats on pain responses in the formalin test and on the number of glial fibrillary acidic protein-immunopositive (GFAP-ip) astrocytes in the caudatoputamen (CPu) and periaqueductal grey (PAG) of these animals. The mean durations of flinch and lifting/biting of the limb...
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