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N-Methyl-2-pyridone-5-carboxamide (2PY) is a major catabolite of NAD, which is excreted in the urine. Assay of plasma concentration and urine exrection of 2PY is of interest for monitoring niacin nutritional state and NAD catabolism. Aging has major impact on number of metabolic processes, but its effect on plasma and tissue 2PY concentration has not been studied so far. The present study was undertaken...
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