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The current work aims to developing MET-CSNPs nanocomposites as drug delivery system. The nanocomposites were prepared by ionic interactions method and optimized using multiple regression analysis. Independent variables included chitosan concentration (CS), tri poly phosphate concentration (TPP) and metronidazole concentration (MET); while dependent variables were percentage loading drug (LE), zeta...
Encapsulation of ginger (Zingiber officinale Roscoe) essential oil (GEO) in different amounts (i.e. 1%, 3%, and 5% v/v) within chitosan nanoparticles (CNPs) was studied. It was done by a two-step method: oil in water emulsion (O/W) and ionic gelation using sodium tripolyphosphate (STPP) as the crosslinking agent. GEO-loaded CNPs appeared to be more aggregated with an increase in the GEO content. An...
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