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Two insulins were isolated from an extract of the Brockmann bodies of channel catfish (Ictalurus punctatus). The primary structure of insulin I is: A-Chain: GIVELCCHKP10 CSLHDLQNYC20 N; B-Chain: GAPQHLCGSH10 LVDALYLVCG20 PNGFFYNPK. Insulin II has three amino-acid substitutions compared with insulin I: A14His to Gln, B1Gly to Val, and B13Asp to Glu. Despite some unusual amino acid substitutions in...
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