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The total synthesis of the naturally occurring cyclic heptapeptide euryjanicins E has been achieved. The euryjanicins E was achieved by applying a two-step solid-phase/solution synthesis strategy. The linear heptapeptide was assembled by standard Fmoc chemistry on the solid phase. Subsequently cyclization was achieved by the solution method. The final product was purified by preparative RP-HPLC, and...
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