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Complexes [Au2(H2Gy3DH)2]Cl2 (1), [Au(H2Gy3Me)]Cl3 (2) and [Au(H2Gy3Et)]Cl3 (3) were obtained with glyoxaldehyde bis(thiosemicarbazone) (H2Gy3DH) and its N(3)-methyl (H2Gy3Me) and N(3)-ethyl (H2Gy3Et) derivatives. The bis(thiosemicarbazones) and their gold(I) and gold(III) complexes exhibited anti-proliferative activity against HL-60, Jurkat (leukemia) and MCF-7 (breast cancer) cells at 10 μmol L−1...
Organic gold complexes have different biological activity, depending on their potential for interactions with key functional molecules.The aim of this study was to investigate potential of several newly synthesized organic gold complexes to influence spontaneous motility of the Fallopian tubes.The effects of [Au(bipy)Cl2]+ (dichloride(2,2′-bipyridyl)aurate(III)-ion), aurothiomalate, [Au(DMSO)2Cl2]Cl...
Nowadays gold nanoparticle (GNP) is increasingly being used in drug delivery and diagnostics. Here we have reported a comparative analysis of detailed stability and toxicity (in vitro and in vivo) profile of three water soluble spherical GNPs, having nearly similar size, but the surfaces of which were modified with three different capping materials aspartic acid (GNPA), trisodium citrate dihydrate...
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