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Simulated moving bed (SMB) chromatography has become the state of the art technology applied for the complex separation tasks in the pharmaceutical and fine chemical industry. Nevertheless, operation of SMB units at their optimal operating conditions is still an issue challenging SMB practitioners due to absence of proper process control schemes. We have developed a feedback control scheme that integrates...
A method for tuning a Pressure Swing Adsorption (PSA) system aimed to achieve symmetrical operating conditions based on pressure differential in the adsorption vessels is developed in this study. Simulation of an oxygen Pressure-Vacuum Swing Adsorption (PVSA) process indicates that the pressure drop inside the adsorption vessel is closely related to the nitrogen concentration and gas velocity. The...
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