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This report concerns a 68-year-old man with an esophageal gastrointestinal stromal tumor (GIST) surgically resected after preoperative treatment. Endoscopic examination and the biopsy revealed the submucosal tumor in the lower esophagus to be c-kit gene positive, and we diagnosed the tumor as a GIST. Computed tomography showed a 124 × 74 × 115 mm mass with an unclear margin adjacent to the posterior...
We report a case of spontaneous submucosal dissection of the esophagus of a 58-year-old patient. In September 2005, he complained of chest pain followed by vomiting. Endoscopy showed an ulcerative lesion in the entire circumference of the middle esophagus. No malignant cells were observed in biopsy specimen. The patient received therapy with hyperalimentation, a proton pump inhibitor, and Alloid G...
Aim Patients with achalasia may have a thicker muscularis propria layer than normal subjects. The aim of our study was to determine the prevalence of increased muscle thickness in patients with achalasia measured by endoscopic ultrasonography (EUS) and evaluation of its relationship with disease characteristics. Methods For a 1-year period we studied 16 nonachalsia patients and 16 consecutive achalasia...
Esophageal perforation with mediastinal abscess formation is a potentially life-threatening complication after chemoradiotherapy (CRT) in patients with esophageal cancer. We present the case of a 64-year-old woman with cervico-thoracic esophageal cancer who had previously undergone distal gastrectomy. Definitive CRT was initially performed since the patient refused laryngectomy. However, she developed...
The consensus meeting was held at the 64th Annual Meeting of the Japan Esophageal Society (JES) in 2010. The majority of the 150 participants were surgeons with a license as a specialist in esophageal surgery or as a certified esophagologist authorized by the JES working in a university hospital or cancer center. Using the answer pad system, each participant chose one answer among three to five answers...
A 54-year-old male undergoing hemodialysis was admitted to our hospital because of difficulty in swallowing. Esophagography and esophageal endoscopy revealed an irregular ulcerated lesion in the cervical esophagus. It was diagnosed as a small-cell esophageal cancer from the biopsy sample. Computed tomography showed a tumor infiltrating the trachea and a few lymph node metastases in the cervix, upper...
Esophageal bronchogenic cyst is a rare congenital malformation. Although thoracoscopic resection is useful, it has not been adopted for esophageal cysts with a large size or severe inflammatory adhesions. We first reported a case of esophageal bronchogenic cyst that was completely resected using endo-staplers during video-assisted thoracoscopic surgery. A 28-year-old man was referred for the treatment...
Changes in the standard treatment for esophageal cancer in Japan are reflected in the history of consecutive studies conducted by the Japan Esophageal Oncology Group (JEOG), a subgroup of the Japan Clinical Oncology Group (JCOG). Following the era of preoperative radiotherapy in the 1970s, the emphasis in surgical adjuvant therapy shifted from postoperative radiotherapy in the 1980s to postoperative...
Background There is no standard second-line chemotherapy regimen after failure of the standard 5-fluorouracil and cisplatin in the treatment of esophageal cancer. We retrospectively investigated the efficacy and toxicity of combination chemotherapy using docetaxel and nedaplatin for patients with metastatic or recurrent squamous cell carcinoma of the esophagus refractory to prior chemotherapy with...
We introduce our novel and original idea of placing a feeding catheter gastrostomy (FCG) at esophagectomy with gastric tube reconstruction through the posterior mediastinal route. The 9-Fr catheter was inserted into the jejunum through the gastric tube by the creation of submucosal and Witzel tunnels on the gastric antrum. Among the 45 patients who underwent FCG, the catheter was guided to the anterior...
Granular cell tumors of the esophagus are rare neoplasms and their diagnosis is mainly based on histopathologic examination of endoscopic biopsies. With the development of endoscopic techniques, there has been a marked increase in local treatment modalities for early esophageal neoplasms. In this case report, we describe the removal of a granular cell tumor by the endoscopic submucosal dissection...
Basaloid squamous carcinoma (BSC) of the esophagus is a rare but distinct variant of esophageal carcinoma, identical to BSC of the upper aerodigestive tract. The incidence of BSC has been reported to present 0.4–3.6% of total esophageal malignant tumors. The average age of BSC patients was 64 years, ranging from 42 to 87 years, with male predominance (male to female ratio 6.8:1). The tumor preferentially...
Most esophageal cancers are either squamous cell carcinomas or Barrett’s mucosa-derived adenocarcinomas. A 64-year-old man with a long history of alcohol drinking and smoking was found to have a tumor in the cervical esophagus on screening esophagography. Subsequent work-up revealed double primary cancer of the esophagus consisting of adenocarcinoma arising from ectopic gastric mucosa in the cervical...
Esophageal cancer rarely metastasizes to the brain. The authors experienced a case of esophageal carcinoma which metastasized to the cerebellum as the first presentation. A 61-year-old man was identified as having esophageal carcinoma by esophagogastroduodenoscopy during a medical checkup. Subtotal esophagectomy with dissection of 3 regional lymph nodes was performed. The tumor was 30 × 20 mm2 in...
Some patients with nonhematopoietic tumors show leukocytosis and pyrexia without overt inflammation. This report describes the case of a 47-year-old Japanese man who complained of persistent fever. Hematological examination showed marked leukocytosis with neutrophilia and elevation of C-reactive protein (CRP). Esophagogastroduodenoscopy demonstrated a polypoid tumor (5 cm in length) in the thoracic...
Background and Aim Nizatidine and itopride hydrochloride inhibit cholinesterase activity and increase acetylcholine in the cholinergic nervous systems. The effect of nizatidine and itopride hydrochloride on esophageal motor function has not been determined, although these drugs are reported to increase gastric motility. Esophageal peristalsis between the upper esophageal sphincter and lower esophageal...
Although occurring infrequently, esophago-mediastinal fistula is potentially life-threatening. We report a rare case of intractable esophago-mediastinal fistula following thoracoabdominal aortic replacement. A 62-year-old male patient with aortic dissection underwent thoracoabdominal aortic replacement. He suddenly developed septic shock with esophageal perforation on the 6th postoperative day. Conservative...
Background Patients undergoing minimally invasive esophagectomy (MIE) may benefit from lower respiratory complications and total morbidity compared with those undergoing open transthoracic esophagectomy (OTE) according to a recent meta-analysis. Local recurrence rates after MIE need to be determined for an assessment of complete resection. The aim of this study was to investigate whether MIE is effective...
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