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Endoscopic submucosal dissection (ESD) has gradually gained acceptance as one of the standard treatments for esophageal squamous cell carcinoma in Japan. Principal indications are little likelihood of nodal metastasis and having technical resectability. All lesions with preoperative diagnosis of high-grade intraepithelial neoplasms, including carcinomas in situ (T1a-EP), carcinomas invading the lamina...
We report a rare case of verrucous squamous cell carcinoma (VSC) of the esophagus. A 73-year-old woman presented to our hospital with dysphagia. On gastrointestinal endoscopy, a white mass with a cauliflower-like appearance (3.5 cm in diameter) was detected in the upper esophagus at 23 cm from the incisors. Histological examination of a biopsy specimen revealed squamous epithelial hyperplasia and...
Primary malignant melanoma of the esophagus (PMME) is a rare disease. Most patients are diagnosed at an advanced stage and few at an early stage. We report a patient with multiple early-stage PMME (tumor invasion was limited to the mucosa, and no lymph node metastasis was detected). Despite initial endoscopic treatment followed by systemic chemotherapy, frequent multiple metachronous lesions occurred...
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