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A method, combining laboratory scale equilibrium and elution experiments, simplified model based and heuristic rules, as well as sophisticated dynamic simulation was applied to design the separation of a two-component steroid crude mixture in a given laboratory-scale Simulated Moving Bed unit. The adsorption equilibrium isotherms of the pure components were determined by Frontal Analysis method. Langmuir...
Aqueous solutions of DL--phenylalanine from a biotechnological process have been desalted by simulated moving bed preparative liquid-chromatography (SMB LC). During the design of a laboratory-scale continuous procedure four kinds of reversed-phase polymeric resin were compared. A suitable adsorbent was chosen and operating conditions were subsequently optimized by using equilibrium data obtained experimentally;...
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