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The design of an intensity modulated radiotherapy treatment includes the selection of beam angles (geometry problem), the computation of an intensity map for each selected beam angle (intensity problem), and finding a sequence of configurations of a multileaf collimator to deliver the treatment (realization problem). Until the end of the last century research on radiotherapy treatment design has been...
In this paper, we propose a linear programming-based method suitable for precise and reliable estimation of the skew of a slave clock respective to a master clock using timing information carried over an asynchronous packet network. Solving this problem is key to the viability of deploying low-cost IP-based transport technology in existing GSM networks. The paper is concluded by empirical evidence...
This is a summary of the author’s PhD thesis, supervised by Yaroslav D. Sergeyev and defended on May 5, 2006, at the University of Rome “La Sapienza”. The thesis is written in English and is available from the author upon request. In this work, the global optimization problem of a multidimensional “black-box” function satisfying the Lipschitz condition over a hyperinterval with an unknown Lipschitz...
We propose an exact branch-and-bound algorithm for the problem of maximizing the minimum machine completion time on identical parallel machines. The proposed algorithm is based on tight lower and upper bounds as well as an effective symmetry-breaking branching strategy. Computational results performed on a large set of randomly generated instances attest to the efficacy of the proposed algorithm.
This is a summary of the author’s PhD thesis supervised by Lionel Amodeo and Hoaxun Chen and defended on 29 November 2005 at the Université de Technologie de Troyes (France). The thesis is written in French and is available from the author upon request. This work deals with a new stochastic Petri net model and its applications for modeling and studying logistics systems and more generally discrete...
Variable neighbourhood search (VNS) is a metaheuristic, or a framework for building heuristics, based upon systematic changes of neighbourhoods both in descent phase, to find a local minimum, and in perturbation phase to emerge from the corresponding valley. It was first proposed in 1997 and has since then rapidly developed both in its methods and its applications. In the present paper, these two...
The two-dimensional level strip packing problem (2LSPP) consists in packing rectangular items of given size into a strip of given width divided into levels. Items packed into the same level cannot be put on top of one another and their overall width cannot exceed the width of the strip. The objective is to accommodate all the items while minimizing the overall height of the strip. The problem is ...
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