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Background The adaptation of steroid therapy and the effect of renin–angiotensin–aldosterone system inhibitors (RASIs) for advanced immunoglobulin A nephropathy (IgAN) patients with impaired renal function are still controversial. Methods We divided 63 IgAN patients with an estimated glomerular filtration rate (eGFR) of <60 ml/min/1.73 m2 and proteinuria ≥ 0.5 g/day into two groups: the RASI...
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