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Introduction The recombinant human bone morphogenic protein-2 (rhBMP-2) is known to increase the proteoglycan production and chondrogenic gene expression in the disc cells. The transforming growth factor-beta 1 (TGF-β1) can transform the bone marrow stem cells (BMDCs) into the disc-like cells. Materials and methods We carried out an experiment to determine if TGF-β1 and rhBMP-2 can act in synergy...
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