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Calcium-activated chloride channels are expressed in chemosensory neurons of the nose and contribute to secretory processes and sensory signal transduction. These channels are thought to be members of the family of anoctamins (alternative name: TMEM16 proteins), which are opened by micromolar concentrations of intracellular Ca2+. Two family members, ANO 1 (TMEM16A) and ANO 2 (TMEM16B), are expressed...
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