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Abstract. The primary secretion formed in various exocrine glands has a [K+] 25times that of plasma. In this study we measured the transepithelial flux of 36Cl, 22Na+ and 42K+ across the frog skin and applied the single-channel patch-clamp technique to the apical membrane of frog skin gland acini to investigate the pathway taken by K+ secreted by the glands. Transepithelial K+ secretion was active...
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