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The high concentration of HCO3 ions (150mM) in the human pancreatic ducts raises the question of the membrane proteins responsible for their secretion in addition to the Cl/HCO3 exchanger. In this study, we investigated the expression of carbonic anhydraseIV (CAIV), a possible candidate. Experiments were carried out on specimens of normal human pancreas obtained from brain-dead donors (n=9) as well...
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