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Das unzureichende Therapierepertoire für RA (rheumatoide Arthritis)-Patienten hat in den 80er-Jahren des letzten Jahrhunderts aufgrund zunehmender Erkenntnisse der der Krankheit zugrunde liegenden pathogenetischen Mechanismen zu der Entwicklung vielfacher neuer und biologischer Therapieverfahren geführt. Wie dargestellt, wurden in der Frühphase der Anwendung biologischer Medikationen zahlreiche zelluläre...
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