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Purpose This study assessed the cardiovascular safety of cabazitaxel, based on thorough evaluation of QT and non-QT variables, and the relationship between pharmacokinetic and pharmacodynamic electrocardiographic (ECG) profiles and the occurrence of Grade ≥3 cardiovascular adverse events. Methods Patients with advanced solid tumors were treated with cabazitaxel 25 mg/m2 every 3 weeks. Digital ECG...
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