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Background/Objective Abnormal cerebral haemodynamics in very preterm infants undergoing neonatal intensive care have been associated with adverse outcome, but cerebral blood flow (CBF) is difficult to assess at the cotside. Spatially resolved spectroscopy (SRS) continuously measures cerebral tissue oxygen saturation expressed as tissue oxygenation index (TOI, %), and TOI would reflect changes in CBF...
Objective Dopamine is widely used to maintain blood pressure in very preterm infants, but it may affect neurovascular regulation as it crosses the immature blood–brain barrier. We contrasted the relationship between cerebral perfusion and oxygen metabolism in preterm infants treated with dopamine because of hypotension with normotensive controls. Design Prospective observational study in a neonatal...
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