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In kleinen, oft kaum bemerkten Schritten hat sich das Management des systemischen Lupus erythematodes (SLE) in den letzten Jahrzehnten deutlich gewandelt. Das Ziel ist heute, jede Krankheitsaktivität zu stoppen, ohne langfristig mehr als 5 mg Prednisolon täglich zu verwenden. Tatsächlich gilt heute als Therapieziel („treat to target“) die Remission, also eine fehlende Aktivität im SLE-Aktivitätsscore...
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