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Das maligne Melanom ist der bsartigste Tumor der Haut mit weltweit steigender Inzidenz. ber die genetischen Vernderungen, welche die Melanominitiation und -progression auslsen und in Gang halten, ist wenig bekannt. Mutationen von p16 (CDKN2), p53, ras, Neurofibromatose Typ I (NF-1), bcl 2 und dem Retinoblastom-Gen (Rb) wurden beschrieben, liegen jedoch smtlich nur in relativ geringen Prvalenzen bezogen...
Keywords:
FUUML;R DIE UUML;BERLASSUNG DER ABB.NBSP;5. MEIN BESONDERER DANK GILT DARUUML;BERHINAUS ANNA KATHARINA BECK FUUML;R DIE SORGSAME DURCHSICHT DES MANUSKRIPTES.RID=ID= E6DR. O. SWENSSON/E6 UNIVERSITAUML;TS-HAUTKLINIK KIEL
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