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In mehreren Multizenterstudien wurde bei mehrmonatiger Gabe von Zykloxygenase- (Cox-)2-Inhibitoren ein signifikanter Anstieg thrombembolischer Komplikationen (Myokardinfarkte und Apoplexe) festgestellt. Im Februar 2005 wurden daraufhin die Kontraindikationen und Anwendungsbeschränkungen für alle Cox-2-Inhibitoren von der Europäischen Arzneimittelagentur (EMEA) erheblich erweitert. So ist ihr Einsatz...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.