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Objective and design The objective of this paper is to elucidate the factors contributing to the development and regression of trehalose 6,6′-dimycolate (TDM)-induced model of tuberculous granulomatous lesions. Materials and treatment BALB/c mice were twice injected i.p. with a 100 μl of w/o/w emulsion (100 μg of TDM, 3.2 μl of Freund’s incomplete adjuvant, 3.2 μl of PBS, and 93.6 μl of saline containing...
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