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Spatial skills have an influence on surgeon's performance during robot-assisted surgery, and as such should be part of the training. Yet, there is a gap between the current training programs for surgical skills and the needed training of crucial spatial skills.
We present a system engineering approach to a problem of DNA damage-repair in human cells. We discuss chosen control systems existing in the cells and demonstrate that they constitute an almost perfect fault tolerant system. We discuss the consequences of gaps in this system and explain why it cannot be completely perfect.
For an implantable system for the recording of brain signals from neonatal mice the design specifications for the weight and the size of a implantable system are very tough. The animals are very small and light weight (1–3 cm, 2– 3 g) and the recording data rate is very high (3,5 Mbit/s). Thus, the system has to be extremely small. With state of the art technique it is not possible to set up a wireless...
Amblyopia is a common visual related eye disease in childhood. Although traditional treatment to amblyopia is effective, there are still some disadvantages, such as poor compliance, easily leading to the healthy eyesight problem, the poor recovery of binocular and stereoscopy vision, the lack of objective parameter guidance, etc. Therefore, a new personalized amblyopia treatment solution is put forward...
We introduce a model-based approach for computationally efficient signal detection and discrimination, which is relevant for biological signals. Due to its low computational complexity and low memory need, this approach is well-suited for low power designs, as required for medical devices and implants. We use linear state space models to gain recursive, efficient computation rules and obtain the model...
Transdermal administration might be an interesting alternative to current routes of administration. It is non-invasive, avoids gastric side effects, and improves bioavailability of the molecules. However, due to the low permeability of the stratum corneum, a permeation enhancement strategy is required to make a large number of molecules suitable to this mode of administration. To overcome those limitations...
Reliable mechanical properties of trabecuale are needed at the tissue-level for prediction of mechanical behavior of the overall trabecular structure using Finite element analysis (FEA). The aim of this study was to develop a set-up to test trabeculae in tension in a close to physiological environment, and to determine reliable tissue-level properties. Ten bovine trabeculae were tested until failure...
The design and simulation of some proposals of unconventional and conventional dental implants and their results are presented. The process of obtaining models with reverse engineering in Mimics, mechanical simulations in ANSYS and some results and tests with an algorithm of remodeling meant to simulate the behavior of the possible influence of stem cells in the proposed implants are explained.
Knee osteoarthritis (OA) is one of the most widespread orthopedic disease that affects the elderly. The present study aims to evaluate the biomechanical effects of bilateral osteoarthritis on elderly patients compared to a control group using stabilometry parameters. The used parameters were center of pressure (CoP) 95% confidence ellipse area, CoP path length and maximum path velocity, CoP range...
Gait analysis gets more accessible, accurate, and simple to use as technology advances. The goal of this paper is to explore the accuracy of an advanced optical motion analysis system, where marker clusters mounted on rigid shapes are used to track the movement of body segments. It aims to examine the magnitude and nature of variation of the angular gait parameters of the lower extremities, caused...
It is well-known that improvements in seat comfort are needed as a medical solution to prevent pressure ulcers. In recent years, pressure ulcers have become an increasing social and medical issue and manufacturers are trying to respond appropriately for better solutions. The contact interaction between human buttock-tissue and seat cushion is an important factor in users' sense of comfort. In this...
This paper investigates the effect of the anorectal angle on continence using a physical model of the anatomical system. A method to fabricate, measure and control a physical model for the simulation of human faecal continence is presented. A model rectum and associated soft tissues, based on geometry from an anonymised CT dataset, was fabricated from silicone and showed behavioural realism to ex...
Human balancing on a balance board is modelled as a delayed proportional-derivative control mechanism with unknown feedback delay. The mechanical model implies that there exists a critical delay, for which no control gain parameters can stabilize the system. This theoretical critical delay is determined by numerical analysis for different geometries of the balance board. Then the results are compared...
Brain computer interface (BCI) systems have ushered a new era of neural engineering research. At the core of BCIi research is development of data acquisition, filtration and classification techniques that can accurately decode the brain activity that occurs while performing a motor task. In this study, we investigate the classification accuracy of lda, QDA, Naïve Bayes, quadratic SVM and RBF SVM classifiers...
The present study aims to determine the effect of professional sailing on the balancing ability compared to a control group using ultrasound-based provocation tests on a moving platform. The balancing capacity after sudden unidirectional perturbation is characterized by following parameters: the damping time (T), the Lehr's damping ratio (D), the orientation ratio (R) and the HeadPath during double-limb...
We analyzed the characteristics of diabetes-related macrovascular complications with the objective of more effectively preventing later lethal complications involving cerebral infarction. The associated diseases of approximately 8,000 diabetic patients and >50,000 non-diabetic individuals were evaluated. The distribution characteristics of the four major vascular complications, hypertension, hyperlipemia,...
In this paper a technique for detecting the daily fatigue using the characteristics of local facial image is discussed. To reduce the influence of environment illumination and retain more details of features, the images are preprocessed by the method of color consistent area correction. The texture and color features are derived from the gray level co-occurrence matrix and two kinds of color space,...
Neurological assessment is a commonly mental screening evaluation for initial neurological disorders in patients. Mild Mental Status Examination is a standard screening test which is used as one of the tools for diagnosis. In Thailand, Thai Mental Status Examination was used to screen the Thai-patients.
Human liver plays a major role in metabolizing medications. One of its metabolic roles is to activate prodrugs into their active form enzymatically. The proposed structure below can be considered as a basic concept of utilizing a liver-on-a-chip for evaluating drug response. One example that of paramount interest to cardiologists is the variable response of their patients to an antiplatelet agent...
Measurement of the activated clotting time (ACT) is an important and regularly performed task in hospitals for thrombosis prevention. Required adjustments of anticoagulation therapy are most often done manually by using a therapeutic look-up table adapted to patient weight. This process is prone to human errors and an automated solution for calculating the required change and readjusting the individual...
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