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This presentation will review the latest linear microscopy techniques applied to imaging the living retina, as well as the normal and pathological retinal structures that can now be visualized non-invasively. This presentation will review the latest linear microscopy techniques applied to imaging the living retina, as well as the normal and pathological retinal structures that can now be visualized...
Deep tissue multiphoton microscopy (MPM) using solitons generated from optical fibers are reviewed. The main characteristics of the excitation source for deep tissue MPM, such as wavelength, pulse energy, and repetition rate, are discussed.
First-principles calculations show that phonon-assisted Auger recombination and its interplay with the polarization fields in polar nitride LEDs play an important role in the efficiency-droop and green-gap problems of these devices.
We present local investigations of the spectral evolution of ultrashort slow pulses as they propagate. We also show that nanoscale electrical and magnetic fields can be detected simultaneously.
The non-uniform electric field in the active regions of an interband cascade laser is directly imaged and characterized for the first time by employing a nanoscopic voltage profiling technique.
We propose a new tool for scaling the speed of arbitrary patterned illumination by two-dimensional spectral-encoding. A multi-objective optimization based on genetic algorithm is presented for its utility in different imaging modalities.
We present the need for new ultrasonic detectors in photoacoustic microscopy and report on the development of a cover-slip type, optically transparent, all-optical ultrasonic detector based on a polymeric micro-ring resonator for various photoacoustic applications.
We demonstrate a new two-photon scanned light-sheet microscopy with diffraction-limited thickness and tailorable illumination area from 50×50 µm2 to 500×500 µm2, capable of multi-scale live imaging in one setup.
We demonstrate that temporal focusing microscopy with structured illumination provides super-resolution even if wavefront distortion within the sample results in stretching the point spread function of the microscope.
We fabricated silicon nanorods on silica substrates, and show that they support electric and magnetic resonances by simulation and experiment. Due to these resonances, the nanorods appear vivid colors when observed by optical microscopy.
Wafer-scale nano-mushroom sensor was demonstrated with the refractive index sensitivity of 373 nm/RIU, resulting in significant color shift detectable by eye. It also works for surface-enhanced Raman spectroscopy with the enhancement factor of 107.
We combine ultrafast multi-terahertz spectroscopy and near-field microscopy to achieve sub-wavelength spatial (∼15 nm) and sub-cycle temporal (∼9 fs) resolution. We apply our novel system to photoexcited InAs nanowires and resolve femtosecond carrier dynamics - spatially, temporally and spectrally.
One of the central assumptions in quantum electrodynamics is to invoke the dipole approximation because (quantum) emitters are much smaller than the wavelength of light. The main consequence is that only the electric dipole plays a role in light-matter interactions at optical frequencies. In this paper we show that semiconductor quantum dots possess large magnetic-dipole and electric-quadrupole moments,...
We demonstrate tunable soliton generation in excess of 3 MW peak power in the 1,700 nm spectral region using a solid-core photonic crystal rod pumped by a compact femtosecond fiber source. This system can potentially be used for in vivo deep tissue multiphoton microscopy.
Using ultrafast optical-pump terahertz-probe spectroscopy, we study the THz dynamics and electronic cooling in few-layer epitaxial and CVD graphene; a microscopic theory of carrier-carrier and carrier-phonon interactions accounts quantitatively for the observed dynamics.
We demonstrate a novel device, based on wedge prisms, that enables simultaneous imaging and fluorescence microscopy of multiple color channels and is simpler, more user-friendly, and less expensive than current commercial devices. Applications include ratiometric calcium imaging and co-localization of multiple labels.
A hyperspectral stimulated Raman microscopy system using rapidly wavelength swept lasers is presented. Imaging of biological samples with shot noise limited detection is demonstrated with the fiber based setup.
I will review our development and application of fluorescence lifetime imaging implemented in microscopy, tomography and endoscopy to provide molecular readouts across the scales from super-resolved microscopy through imaging of disease models to clinical applications.
We report on position and density control of nitrogen-vacancy (NV) centres created in type Ib diamond using localised exposure from a helium ion microscope and subsequent annealing. Spatial control to <380 nm has been achieved.
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