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This paper proposes few improvements to “Hybrid Neuro Fuzzy Genetic System (HNFGS)”, which we have implemented and presented in [13] for protein secondary structure prediction. The hybridization of artificial neural networks, genetic algorithms, and fuzzy logic can produce robust solutions for complex prediction problems, such as protein secondary structure prediction. Due to the complex and dynamic...
Protein multiple sequence alignment is a fundamental task in bioinformatics. Its importance is due to its application in the estimation of the phylogeny tree, prediction of the secondary and tertiary protein structure, function prediction and finding motifs among protein sequences. Obtaining the best solution in multiple sequence alignment (MSA) is an NP-hard problem and whose speed and accuracy researchers...
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