The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Tagged magnetic resonance imaging (MRI) has the ability to directly and non-invasively alter tissue magnetization and produce tags on the deforming tissue [1], [2]. Since its development, the Spatial Modulation of Magnetization (SPAMM) [2] tagging pulse sequence has been widely available and is the most commonly used technique for producing sinusoidal tag patterns. However, SPAMM suffers from tag...
Several risk score models are available in literature to predict death/myocardial infarction event for coronary artery disease (CAD) patients, within a short period of time. However, the choice of the most adequate model is not straightforward since there might not be a consensus about the best model to use in clinical practice Moreover, individually, these models present some weaknesses, such as...
Acute myocardial infarction (AMI) diagnosis in type II diabetes (DM2) patients is difficult and ECG findings are often non-diagnostic or inconclusive. We developed computer algorithms to process standard 12-lead ECG input data for quantitative 3-dimensional (3D) analysis (my3KGTM), and hypothesized that use of the my3KGTM's array of over 100 3D-based AMI diagnostic markers may improve diagnostic accuracy...
Myocardial infarction (MI), generally known as a heart attack, is one of the top leading causes of mortality in the world. In clinical diagnosis, cardiologists generally utilize 12-lead ECG system to classify patients into MI symptoms: 1. ST segment elevation, 2. ST segment depression or T wave inversion. However unstable ischemic syndromes have rapidly changing supply versus demand characteristics...
By combining a static bidomain heart model with a torso conduction model, we studied the inverse elec-trocardiographic problem of computing the transmembrane potentials (TMPs) throughout the myocardium from a body-surface potential map, and then used the recovered potentials to localize myocardial ischemia. Our main contribution is solving the inverse problem within a constrained optimization framework,...
Ventricular arrhythmias represent one of leading causes for sudden cardiac death, a significant problem in public health. Noninvasive imaging of cardiac electric activities associated with ventricular arrhythmias plays an important role in better our understanding of the mechanisms and optimizing the treatment options. The present study aims to rigorously validate a novel three-dimensional (3-D) cardiac...
Transmural myocardial activation is influenced by myocardial structure, including structural differences between the compacta (Cta) and the trabeculata (Tta), although this has not been fully explained. Hearts from rats were Langendorff perfused, stained with DI-4-ANEPPS, the apex was cut off and fluorescence acquired from the exposed short-axis surface. The hearts were stimulated at 160 ms cycle...
This paper presents and evaluates preferred patterns of vibrations and active breaking techniques for the Diastolic Timed Vibrator (DTV). DTV uses low frequency mechanical vibrations applied to the chest to help in clot dissolution in pre-hospitalization treatment of acute coronary ischemia. In this work, we argue that random and ramp type vibration patterns increase the performance of the DTV method...
Measurements of myocardium tissue impedance during the cardiac cycle have information about the morphology of myocardium cells as well as cell membranes and intra/extra cellular spaces. Although the variation with time of the impedance cardiac signal has information about the myocardium tissue activity during the cardiac cycle, this information has been usually underestimated in the studies based...
A method of non-rigid image registration was developed and evaluated for the purpose of quantifying myocardial displacement and strain from cine MRI using DENSE MRI as the reference standard. The objective of this paper was to study the potential use of cine MRI with image registration, as a means of measuring strain. The local displacement of the left ventricle was modelled by free-form deformations...
Magnetic resonance imaging (MRI) has long been recognized as a powerful tool for cardiovascular imaging because of its unique potential to measure blood flow, cardiac wall motion and tissue properties jointly. However, many clinical applications of cardiac MRI have been limited by low imaging speed. Three-dimensional cardiovascular MRI in real-time, or 4D cardiovascular MRI without cardiac and respiratory...
Congestive heart failure is a leading cause of morbidity and mortality in the United States and worldwide [1]. Although not the only cause of congestive heart failure, loss of myocardium due to obstructive coronary artery disease is a major contributor to this condition [2,3]. The loss of myocardium is mainly regional and, therefore, localized therapy holds the most promise. In recent years, many...
The effect on acid-base balance efficacy of intermittent warm and cold blood cardioplegia (IWBC, ICBC) was assessed in 44 patients who underwent cardiac surgery with prolonged aortic cross clamping. With this purpose a customized multi sensor probe was inserted in the coronary sinus, and pH, PO2, PCO2 and temperature were continuously measured at 1 Hz sampling rate. The mean cross-clamping time was...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.