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High drug loading (DL) carrier is an effective way to cure the cancerous cells. High drug loading is also one of the key issues in the drug delivery research, especially the colonic drug delivery system by oral administration. The times of drug intake could be remarkably reduced if high drug loading carriers are administered. At the same time, the related formulation materials could be effectively...
Glucomannan extracted from konjac was sulfated (konjac oligo-glucomannan sulfate, OGMS) to show selective anti-hepatitis B virus activity in vitro using HepG2–2.2.15 cell line as the host cell of Hepatitis B virus. OGMS straight inhibited the secretion of HBsAg, HBeAg and HBV-DNA Replication in HepG2–2.2.15 cell by ELISA and FQ-PCR. The studies indicated that OGMS mainly acted as an HBsAg inhibitor...
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